Our research program investigates neurocognition in serious mental illness, such as mood disorders and psychotic disorders. We are focused on understanding the biological mechanisms and environmental factors that contribute to the development of cognitive deficits, as well as testing novel therapies that may improve such impairments.

Project 1: Identifying Immune Mechanisms Underlying Differential Neurocognitive Trajectories in Bipolar Disorder

This study, an extension of project 2 listed below, is a 36-month longitudinal study with an added focus on immune dysfunction as it is thought to contribute to cognitive and functional decline.

For more information on participating, please visit

Project 2: Brain-based Mechanisms of Emotion Regulation in Aging and Mood Disorders

Emotion regulation (ER) refers to the ability to flexibly and dynamically respond to affectively-valenced stimuli in the service of goal-directed behaviors. Difficulties with ER are core to mood disorders. We will assay habitual use of ER strategies, social functioning, and well-being in 200 adults to determine how brain-based processes affect functionally- and clinically relevant outcomes.

For more information on participating, please visit



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